导致老年人运动受限的临床和生理风险因素:纵向分析
Xin Jiang1,2,3, Huiying Tan4,5, Huixia Ren4,5,6
1Department of Geriatrics, Shenzhen People's Hospital, Shenzhen, Guangdong, China. jiangxinsz@163.com.
BMC geriatrics
|July 25, 2024
概括
老年人有跌倒史,不控制高血压,步行速度较慢,日常生活活动 (ADL) 评分较低,面临更高的运动限制风险. 这些因素对于制定有针对性的干预措施,以保持老龄化人口的独立性至关重要.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 移动性限制对老年人的功能独立性和生活质量产生重大影响.
- 移动性受到神经生理学和社会人口学因素的复杂相互作用的影响.
- 识别行动限制的预测因素对于老龄化人口的积极健康管理至关重要.
研究的目的:
- 调查各种基线特征与老年人发展限制运动的风险之间的关系.
- 确定关键的神经生理学,社会人口学和功能因素,与未来的移动性限制相关.
- 为制定有针对性的干预措施提供信息,以维持老年人的流动性.
主要方法:
- 一项纵向研究涉及668名年长的成年人,在基线时具有完整的运动能力.
- 基线评估包括临床因素,认知功能 (MoCA),睡眠质量 (PSQI),ADL,步行表现,血压和脑MRI.
- 后勤回归分析检查了基线特征和18个月后的移动性限制之间的关联.
主要成果:
- 运动受限的老年人年龄较大,ADL和MoCA得分较低,睡眠质量较差 (PSQI),血管功能较差,步行速度较慢.
- 跌倒史,不受控制的高血压和更高的Fazekas尺度得分是限制移动性的重要预测因素.
- 较慢的步行速度和较低的ADL得分在基线也增加了未来移动性限制的风险.
结论:
- 血管特征,精神认知功能和运动性能是老年人发展限制运动能力的关键风险因素.
- 这些发现强调了多因素方法对评估流动性风险的重要性.
- 鉴定的风险因素可以指导临床和康复计划的设计,以促进老年人群的流动性和独立性.
相关概念视频
Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
Aging
41
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
41
Factors Affecting the Risk of Infection
11.5K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.5K
Factors Affecting Illness
4.2K
When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness,...
For instance, risk factors are connected to illness,...
4.2K
Factors Affecting Renal Clearance: Renal Impairment
71
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
71
Factors Affecting Protein-Drug Binding: Patient-Related Factors
50
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
50


