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移植患者勃起功能障碍的时间依赖性分析:来自四个不同的时间段的见解
Jiashan Pan1,2,3, Zhenming Zheng1,2,3, Wenbo Wang1,2,3
1Department of Urology, The First Affiliated Hospital of Anhui Medical University, Jixi Road 218Th, Shushan District, Hefei, Anhui, 230022, China.
BMC infectious diseases
|July 25, 2024
概括
移植改善了男性接受者的勃起功能障碍 (ED). 然而,由于新的风险因素,ED在COVID-19后恶化,需要针对性的预防和管理策略.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 安德罗学与人类学
背景情况:
- 勃起功能障碍 (ED) 是一种普遍影响男性移植接受者 (mKTRs) 的疾病.
- 了解ED在不同健康阶段的动态分布对于患者护理至关重要.
研究的目的:
- 为了比较四个不同时期的mKTR中ED的患病率和严重程度:末期病 (ESRD),移植后早期 (EPTP),COVID-19前和COVID-19后.
- 在mKTR中识别与ED相关的风险因素,特别是在COVID-19后的时代.
主要方法:
- 数据是通过采访,随访和230个mKTR的医疗记录收集的.
- 使用国际勃起功能指数问卷-5 (IIEF-5) 评估勃起功能.
- 统计分析包括曼·惠特尼U,奇平方,单变量和后勤回归来确定ED的流行率和风险因素.
主要成果:
- 脏移植 (KT) 后勃起功能得到改善,正常功能从ESRD增加到EPTP.
- 在COVID-19后的时期,与EPTP和COVID-19前相比,勃起功能显著下降.
- 流行后的ED风险因素包括焦虑,捐赠者类型,术后时间,高血压和血红蛋白水平.
结论:
- 移植通常会在五年内改善男性接受者的勃起功能.
- COVID-19大流行对mKTRs的勃起功能产生了负面影响,与改变的风险因素有关.
- 调查结果强调了针对mKTRs量身定制的ED预防和管理策略的需要,特别是考虑到与流行病相关的变化.
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