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急性损伤对社区的影响
Javier Diaz1, Laura Lidon1, Inma Sauri1
1Big Data and Artificial Intelligence Group Incliva Research Institute, Spain.
概括
急性病 (AKD) 和急性损伤 (AKI) 发作很常见,并增加患慢性病 (CKD) 和死亡的风险. 对于幸存者来说,早期识别和跟进非常重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 急性病和乱 (AKD) 和急性损伤 (AKI) 是一个重要的健康问题.
- 在AKD/AKI发作后,功能障碍和死亡率的进展需要进一步的社区评估.
研究的目的:
- 为了确定AKD和AKI在一般人群中的发病率.
- 评估AKD/AKI对慢性病 (CKD) 进展的影响.
- 评估AKD/AKI发作与全因死亡率之间的关联.
主要方法:
- 利用来自超过180万成年人社区队列的数据,至少有两次血清肌素测量.
- 通过使用协调的KDIGO标准和RIFLE尺度来定义CKD,AKD和AKI.
- 分析了功能障碍的进展和AKD/AKI发作后的死亡率.
主要成果:
- 在4.8年内,在47972名患者中确定了56850次AKD发作;在CKD患者中,发病率更高.
- 在没有CKD的患者中,很大一部分 (43.8%) 在AKD发作后进展为CKD.
- 在AKD的3个月内死亡率为7%,在AKI的30.1%,预先存在CKD的患者的死亡率更高.
结论:
- 血清肌素急性升高 (AKD/AKI) 在社区中构成重大健康风险.
- 这些情节与CKD的发展和进展有关.
- 针对AKD/AKI幸存者的有针对性的干预和后续治疗是必不可少的.
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