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Updated: Jun 19, 2025

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
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释放选择性CDK7和BRD4抑制对多发性髓瘤细胞生长的治疗潜力

Yao Yao1, Shuhui Deng2, Jessica Fong Ng3

  • 1Jerome Lipper Multiple Myeloma Disease Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Blood Disease Institute, Key Laboratory of Bone Marrow Stem Cell, Xuzhou Medical University, Xuzhou, China; The Affiliated Hospital of Xuzhou Medical University, Xuzhou.

Haematologica
|July 25, 2024
PubMed
概括

针对CDK7和BRD4一起显示出治疗多发性骨髓瘤 (MM) 和沃尔登斯特罗姆巨型球蛋白病 (WM) 的前景. 这种组合疗法有效地减少了癌细胞的生长,并诱导了细胞亡,提供了潜在的新治疗策略.

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