对约旦一家高等教学医院的药监数据注册表进行了回顾性分析
Khawla Abu Hammour1, Faris El-Dahiyat2, Rund Hyari3
1Department of Biopharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, The University of Jordan, Amman, Jordan.
Journal of pharmaceutical policy and practice
|July 25, 2024
概括
约旦大学医院的药物不良反应 (ADR) 报告增加,大多数ADR不是严重的. 加强药物监测,特别是药剂师的药物监测,对于患者的安全至关重要.
科学领域:
- 药物监督 药物监督 药物监督
- 药品安全 药品安全
- 临床药房 临床药房
背景情况:
- 药物不良反应 (ADRs) 对全球患者安全和医疗保健系统构成重大威胁.
- 有效的药物监测系统对于监测药物安全性和减轻与药物使用相关的风险至关重要.
- 了解当地ADR报告模式对于定制干预措施和改善特定医疗保健环境中的药物安全实践至关重要.
研究的目的:
- 分析约旦大学医院的药物不良反应 (ADR) 报告模式.
- 确定ADR的趋势,包括人口统计,涉及的药物和受影响的器官系统.
- 提供数据驱动的建议,以加强药物监督实践.
主要方法:
- 对2月至2023年8月在约旦大学医院收集的ADR报告进行了回顾性分析.
- 数据提取包括患者人口统计,药物细节,副作用的严重性和受影响的系统器官类别.
- 使用WHO-UMC系统进行了因果关系评估.
主要成果:
- 总共分析了1340份ADR报告,其中女性 (67.4%) 和18-65岁的成年人 (95.3%) 是报告最多的群体.
- 大多数ADR不是严重的 (97.9%),常见症状包括腹痛 (8.3%),恶心 (6.9%),头痛 (4.7%) 和头 (4.7%).
- 心血管 (16.4%) 和食道/代谢 (16.2%) 药物最常与副作用相关,主要是通过口服 (89.5%).
结论:
- 报告ADR的情况显著增加,这表明医疗保健提供者的意识有所提高.
- 加强药物监测,以药剂师的积极参与,对于有效的ADR检测和报告至关重要.
- 建议对严重的副作用进行进一步的研究,以改善患者的安全性和结果.
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