日本红色名单中的物种的基因组组装目录:通过基因组库存解锁危生物多样性
Kirill Kryukov1,2, Naoyuki Nakahama3,4, Shigehiro Kuraku5,6
1Center for Genome Informatics, Joint Support-Center for Data Science Research, Research Organization of Information and Systems, Mishima, Shizuoka, 411-8540, Japan.
F1000Research
|July 25, 2024
概括
全基因组测序数据对于监测遗传多样性至关重要,特别是对于危物种. 然而,日本红色名单上只有2.1%的物种有可用的基因组数据,这凸显了需要更广泛的测序工作的需要.
科学领域:
- 基因组学就是基因组学.
- 保护生物学 保护生物学
- 生物信息学是一种生物信息学.
背景情况:
- 在DNA测序技术的进步导致了跨不同物种的全基因组数据的激增.
- 基因组序列数据对于评估物种内遗传多样性至关重要,这是保护的关键因素.
- 关于受威胁物种的数据,特别是国家红色名单上的数据,往往很少.
研究的目的:
- 评估日本红色清单中列出的物种全基因组序列数据的可用性.
- 确定当前对受威胁的种群的基因组测序工作中的偏见和局限性.
- 为未来的基因组测序政策提供信息,并优先考虑保护基因组学研究.
主要方法:
- 结合了来自日本红色名单的数据和来自国家生物技术信息中心 (NCBI) 的基因组组装记录.
- 对列出的物种进行全基因组序列数据的可用性进行表格化.
- 分析了可用基因组数据在不同分类群体的分布.
主要成果:
- 在日本红色名单上的物种中,只有2.1%的物种有公开可用的全基因组序列数据.
- 存在显著的偏差,主要可用于哺乳动物,鸟类 (动物) 和血管植物 (植物) 的数据.
- 潜在的局限性包括大基因组测序的预算限制,特别是在两动物中.
结论:
- 目前的基因组测序工作不足以充分监测许多危物种的遗传多样性.
- 未来的政策应该解决已识别的偏见,并优先对代表性不足的种类进行测序.
- 该研究为指导保护基因组学倡议和资源分配提供了宝贵的资源.
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