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描述性流行病学早期发病的胃肠道癌症在伊朗,2014-2018年
Mohammad Sadra Gholami Chahkand1, Fatemeh Esmaeilpour Moallem1, Fatemeh Ghasemi-Kebria1
1Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.
Middle East journal of digestive diseases
|July 25, 2024
概括
2014-2018年,伊朗的早期胃肠道癌症 (EOGIC) 发生率显示,结肠直肠癌 (EOCRC) 的趋势在增加,食道癌 (EOEC) 和胃癌 (EOGC) 的趋势在下降,观察到地理差异.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 胃肠道癌症在全球范围内是一个重大的健康问题.
- 早期发病的胃肠道癌症 (EOGIC) 是一个不断增长的研究领域.
- 了解EOGIC的发病率和分布对于有针对性的干预至关重要.
研究的目的:
- 确定伊朗早期食道癌 (EOEC),早期胃癌 (EOGC) 和早期结直肠癌 (EOCRC) 的发病率和地理分布.
- 分析2014年至2018年的EOGIC发病率趋势.
- 为了确定伊朗各省的EOGIC发生的地理差异.
主要方法:
- 在新的EOGIC病例 (2014-2018) 中使用了来自伊朗国家基于人口的癌症注册表 (INPCR) 的数据.
- 使用来自伊朗统计中心的人口数据计算出发病率.
- 每10万人年计算的年龄标准化发病率 (ASR),包括95%的置信区间 (CI).
主要成果:
- 在2014年至2018年期间,共有19679起EOGIC案件被注册.
- 每10万人/年,EOEC的ASR (95% CI) 为0.49 (0.47-0.51),EOGC为1.67 (1.63-1.71) 和EOCRC为3.07 (3.01-3.13) 的人.
- 观察到EOEC和EOGC的下降趋势,EOCRC的上升趋势,以及各省发病率的显著地理差异.
结论:
- 在伊朗,EOCRC的发病率显示出持续的上升趋势.
- 在伊朗各省之间,EOGIC发病率存在显著的地理差异.
- 建议进行进一步的研究,以阐明伊朗EOGIC的时间趋势和风险因素.
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