丸癌幸存者的勃起功能障碍:对病例控制研究的元分析
Jian Xiong1, Jianzhong Zhang1, Zhonglin Cai1
1Department of Urology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Dongcheng District, Beijing, China.
Archives of medical science : AMS
|July 25, 2024
概括
与健康男性相比,丸癌 (TC) 患者面临勃起功能障碍 (ED) 的风险更高. 在治疗丸癌后的短期内,ED的风险更大.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 男人的健康 男人健康
背景情况:
- 丸癌 (TC) 是14-44岁男性中最常见的癌症.
- 勃起功能障碍 (ED) 是TC幸存者的潜在并发症.
- 现有研究表明,TC患者的ED风险不同.
研究的目的:
- 为了估计丸癌患者ED的整体风险.
- 为了比较TC患者和健康对照人群之间的ED发病率.
- 在TC幸存者中分析短期与长期的ED风险.
主要方法:
- 对病例控制研究的元分析.
- 在2019年6月之前搜索了PubMed,EMBASE,Scopus和Cochrane图书馆.
- 包括8项研究,包括2060名TC患者和2651名对照.
主要成果:
- 在TC患者中,ED的风险显著增加 (OR=2.39).
- 勃起障碍发生在16.9%的TC患者中,而对照组为9.4%.
- 短期ED风险 (随访时间<5年) 比长期风险 (OR = 1.61) 高 (OR = 3.76).
结论:
- 丸癌患者患勃起功能障碍的风险较高.
- 在短期内治疗TC后,ED的风险更高.
- 在TC患者中,长期ED风险低于短期风险.
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