优化手持的光谱编码连贯性断层扫描和反射测量,用于点的护理眼科诊断成像
Jacob J Watson1, Rachel Hecht1, Yuankai K Tao1
1Vanderbilt University, Department of Biomedical Engineering, Nashville, Tennessee, United States.
Journal of biomedical optics
|July 25, 2024
概括
手持的光谱编码连贯断层扫描和反射计 (HH-SECTR) 为眼科诊断提供实时视网膜定向和运动校正. 这种改进的系统增强了临床翻译的点的护理成像.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 在光学成像系统中,光学成像
背景情况:
- 手持式光学连贯性断层扫描 (HH-OCT) 便于对具有挑战性的患者群体进行临床眼科成像.
- HH-OCT的临床应用面临由于运动器件和对齐困难的局限性.
研究的目的:
- 为了使HH-SECTR的强大的临床翻译能够用于眼科诊断.
- 提高HH-SECTR的人体工程学和稳定性,以改善护理点成像.
主要方法:
- 重新设计的HH-SECTR与优化的SER面对视网膜准和跟踪.
- 整合了一个模块化形状因子,以提高光学-光机械稳定性.
- 开发了一只手,电动化的焦点调整,以提高可用性.
主要成果:
- 展示了一个具有微米尺度稳定的HH-SECTR探头.
- 在人体视网膜成像中成功进行了体内成像.
- 在成像过程中实现了体积运动校正.
结论:
- 重新设计的HH-SECTR系统提高了眼科诊断的稳定性和可用性.
- 这一进步促进了HH-SECTR在临床应用中的临床翻译.
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