相关实验视频

Updated: Jul 7, 2026

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting
08:40

Production of Pseudotyped Particles to Study Highly Pathogenic Coronaviruses in a Biosafety Level 2 Setting

Published on: March 1, 2019

58.9K

建立和描述一个hACE2/hTMPRSS2敲入小鼠模型来研究SARS-CoV-2

Hongwei Liu1, Terza Brostoff1, Ana Ramirez1

  • 1Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California, Davis, CA, United States.

Frontiers in immunology
|July 25, 2024
PubMed
概括

一种新的人类ACE2 / TMPRSS2敲入小鼠模型允许研究轻度的COVID-19. 这种非致命的模型使得对急性和后急性SARS-CoV-2感染阶段的研究成为可能,为肺部和心血管结果提供了洞察力.

关键词:
在 COVID-19 疫情中,这就是SARS-CoV-2病毒.这是一个敲门式鼠标.鼠标ACE2 是ACE2 的一个类型.鼠标 TMPRSS2 是一个病变的发生和发病.肺功能 肺功能 肺功能病毒 病毒 病毒 病毒

更多相关视频

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines11:32

Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines

Published on: November 13, 2021

10.5K
Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-208:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

2.7K

相关概念视频

Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...