帕拉种子油及其脂肪酸减轻光衰老并维持细胞平衡
Nattaya Lourith1,2, Mayuree Kanlayavattanakul1,2, Mattaka Khongkow3
1School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand.
International journal of cosmetic science
|July 25, 2024
概括
帕拉种子油显示出作为一种新的光衰老保护剂的潜力. 这种植物油通过减少炎症标记物和原降解酶,有效地保护皮肤细胞免受紫外线损伤,提供可持续的抗衰老解决方案.
科学领域:
- 皮肤病学 皮肤病学
- 化品科学 化品科学
- 植物性疗法 植物性疗法
背景情况:
- 帕拉种子油以有益于皮肤和头发的脂肪酸而闻名.
- 它对皮肤光衰老的有效性以前没有被研究过.
研究的目的:
- 评估帕拉种子油在缓解皮肤光衰老方面的潜力.
- 为了研究它的光保护机制,并将其与脂肪酸成分进行比较.
主要方法:
- 在人类HaCaT细胞和皮肤纤维细胞 (HDF) 的共同培养中研究了对种子油.
- 通过监测IL-6,IL-8,MMP-1和MMP-9水平来评估光保护效率.
- 将油的效果与其单个脂肪酸成分进行比较.
主要成果:
- 巴拉种子油在保护共同种植物免受紫外线损伤时的安全性和有效性在100μg/mL时被证明是安全的.
- 该油显著抑制了UV诱导的IL-6,IL-8,MMP-1和MMP-9.
- 它的脂肪酸,尤其是不和C18的脂肪酸,被认为具有光保护作用.
结论:
- 帕拉种子油显示出作为新一代光衰老保护剂的潜力.
- 它可以帮助保持皮肤平衡,并由于其光保护性质减轻衰老.
- 鼓励开发使用这种可持续材料的抗衰老产品.
相关概念视频
The Effect of Aging on Tissues
2.1K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.1K
Lipid-derived Compounds in the Human Body
4.3K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
4.3K
Mitochondria
11.9K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
11.9K
Assembly of the Lipid Bilayer in the ER
3.1K
Biological membranes are more than just a barrier separating cell cytoplasm from the outside environment. They are highly dynamic and help maintain the integrity and physiological stability of the cells as well as membrane-bound organelles. Membranes also play vital roles in cell-to-cell and intracellular communication.
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
3.1K
Peroxisomes
11.7K
Peroxisomes are specialized organelles present in fungi, plant, and animal cells. It can vary in number, size, morphology, and activity depending on the type of tissue and the nutritional state of the cell. For example, cells with active lipid metabolism, such as adipocytes, neurons, and hepatocytes, have more peroxisomes than other cells in the body. Besides their primary role in breaking down complex organic molecules, peroxisomes can also synthesize specific macromolecules and participate in...
11.7K
Fats as Energy Storage Molecules
24.9K
Triglycerides are a form of long-term energy storage molecules. They are made of glycerol and three fatty acids. To obtain energy from fat, triglycerides must first be broken down by hydrolysis into their two principal components, fatty acids and glycerol. This process, called lipolysis, takes place in the cytoplasm. The resulting fatty acids are oxidized by β-oxidation into acetyl-CoA, which is used by the Krebs cycle. The glycerol that is released from triglycerides after lipolysis...
24.9K


