骨髓移植后内生膜炎:一个病例报告和文献综述
Cindy S Zhao1, Karen Wai1, Eubee B Koo1
1Department of Ophthalmology, Byers Eye Institute, Stanford University, Palo Alto, CA 94303, USA.
Vision (Basel, Switzerland)
|July 25, 2024
概括
随着内源性内耳炎的传播性菌病是一种严重的感染在免疫功能低下的患者. 积极的治疗是至关重要的,但对Fusarium endophthalmitis的结果仍然很差.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 血液学 血液学 血液学
背景情况:
- 传播性菌病是一种罕见但严重的真菌感染.
- 免疫抑制,特别是在骨髓移植后,增加了易感性.
- 由于Fusarium物种引起的内源性内甲状腺炎是一个重要的管理挑战.
研究的目的:
- 在免疫功能低下的患者中呈现一种与双边内源性内眼炎相关的扩散性菌病例.
- 审查有关Fusarium endophthalmitis的文献,重点关注管理策略.
- 为了突出治疗这种侵袭性感染的挑战.
主要方法:
- 一个70岁的男性患有急性髓性白血病和骨髓移植的案例介绍.
- 诊断双边的Fusarium内耳炎,真菌病,以及扩散的Fusariosis.
- 关于31个Fusarium endophthalmitis病例的文献综述.
- 分析治疗策略,包括手术干预和抗真菌疗法.
主要成果:
- 这位患者出现视力下降和浮动,诊断为双边的Fusarium endophthalmitis.
- 在皮肤和关节中发现了真菌病和Fusarium感染的证据.
- 尽管用帕斯普拉纳切除术和抗真菌药物 (安福特素,沃里可纳) 进行了积极的治疗,但患者的结果很差.
- 文献综述表明,Fusarium endophthalmitis的结果不佳,强调需要积极的多式联络治疗.
结论:
- 体细菌病和内炎往往是对治疗的反抗性.
- 积极和及时的管理,结合系统和外科手术的方法是必不可少的.
- 对于患有Fusarium endophthalmitis的患者来说,结果仍然不利,这凸显了病情的严重性.
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