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在癌症中,HYENA检测到被远端增强剂激活的瘤基因

Anqi Yu1, Ali E Yesilkanal1, Ashish Thakur2

  • 1Ben May Department for Cancer Research, University of Chicago, Chicago, IL, USA.

Nucleic acids research
|July 25, 2024
PubMed
概括

我们开发了HYENA,这是一个计算工具,用于找到在癌症中通过增强器劫持激活的瘤基因. 这种方法确定了108个候选瘤基因,包括像TOB1-AS1这样的非编码基因,它促进胰腺癌转移.

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