老年男性下尿道症状:前列腺癌检测的考虑因素
Stephen Schmit1, Kamil Malshy1, Anna Ochsner1
1The Minimally Invasive Urology Institute at The Miriam Hospital, Division of Urology, Warren Alpert Medical School of Brown University, Providence, RI, USA, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
The Prostate
|July 25, 2024
概括
在老年男性中,下泌尿道症状 (LUTS) 和前列腺癌 (PCa) 经常并存. 一种系统的方法有助于检测积极的PCa,同时防止过度诊断和过度治疗.
科学领域:
- 老年医学 老年医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
背景情况:
- 低尿路症状 (LUTS) 和前列腺癌 (PCa) 在老年男性中很普遍.
- LUTS可以触发前列腺特异性抗原 (PSA) 测试,可能导致与竞争性健康风险的男性过度诊断PCa.
- 在了解LUTS-PCa关系和老年男性最佳评估策略方面存在差距.
研究的目的:
- 为了澄清LUTS和PC之间的关系,在老年男性中存在风险.
- 概述一种评估老年男性LUTS的方法,以平衡PCa检测,避免过度诊断.
- 改善患者和提供者对在LUTS的背景下PCa风险评估的理解.
主要方法:
- 使用PubMed进行了一项文献审查.
- 在2023年11月之前发表的文章进行了相关性选.
- 关键词集中在LUTS,PCa,老年男性和诊断评估上.
主要成果:
- 在老年男性中,LUTS和PCa在很大程度上看起来独立.
- 目前的PCa风险评估工具 (PSA,生物标志物,成像) 在老年人群中存在局限性.
- 建议对这些患者采取三级评估方法.
结论:
- 老年男性经常出现LUTS和高患病率的惰性PCa.
- 一种系统的,共享的决策方法可以优化攻击性PCa的检测,同时最大限度地减少过度测试和过度诊断.
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