干扰素诱导的蛋白44 (IFI44) 和干扰素调节因子4 (IRF4) 在类风湿性关节炎中的基因表达

Shaimaa Elsayed Ramadan Genena1,2, Maha A F Hamouda1, Norhan M Salama1

  • 1Department of Medical Biochemistry & Molecular Biology, Faculty of Medicine, Menoufia University, Shibin El Kom, Egypt.

概括

过度激活的I型干扰素 (IFN) 途径与自身免疫性疾病有关. 这项研究发现,干扰素诱导蛋白44 (IFI44) 和干扰素调节因子4 (IRF4) 基因表达在类风湿性关节炎 (RA) 患者中升高,IFI44显示出诊断潜力.

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