后COVID综合征的定义和症状:一个更新的系统性总体审查
Julian Gutzeit1,2, M Weiß3,4, C Nürnberger5
1Center of Mental Health, Department of Psychiatry, Psychosomatic and Psychotherapy, University Hospital Würzburg, Margarete-Höppel-Platz 1, 97080, Würzburg, Germany. Gutzeit_j1@ukw.de.
后COVID综合征 (PCS) 研究得到了改进,但定义需要改进. 关键症状包括疲劳,神经问题和运动不耐受,严重影响日常生活.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
背景情况:
- 后COVID综合征 (PCS) 在COVID-19后呈现持续症状,导致全球健康负担很大.
- 早期的流行病研究面临的诊断和治疗的不确定性,由于新型疾病和非特定的定义.
研究的目的:
- 综合审查当前的后COVID综合征定义.
- 确定与PCS相关的普遍症状和功能障碍.
- 评估PCS研究质量和数量的演变.
主要方法:
- 在PubMed系统搜索2022年5月31日至2023年12月31日期间发表的PCS评论和元分析.
- 在95项已识别的研究中,包括33项研究.
- 从选定的研究中系统记录PCS相关症状.
主要成果:
- 疲劳,神经疾病和运动不耐受是PCS最常见的症状.
- 在过去的18个月中,PCS研究的数量和质量显著增加.
- 现有的PCS定义往往缺乏具体性和客观评估标准.
结论:
- 最近的研究表明,在了解后COVID综合征方面取得了进展.
- 进一步细化诊断症状标准对于可比和精确的未来研究至关重要.
- 改进的定义将促进PCS的理解和管理.
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