认知储备和执行功能在双重任务步行的表现在帕金森病
Helena Fernández-Lago1,2,3, Pere Bosch-Barceló4,5, José Andrés Sánchez-Molina6
1Department of Nursing and Physiotherapy, University of Lleida, Lleida, Spain. helena.fernandez@udl.cat.
Experimental brain research
|July 25, 2024
概括
认知储备在帕金森病 (PD) 中没有影响双重任务步态. 然而,执行功能,年龄和疾病严重程度影响了PD患者在复杂任务期间的步行表现.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 运动障碍 运动障碍
背景情况:
- 高等教育与帕金森病 (PD) 中较不严重的运动障碍相关.
- 关于认知储备在PD中复杂的运动性能中的作用的证据有限.
- 了解影响PD双重任务步行的因素对于管理日常活动至关重要.
研究的目的:
- 为了研究认知储备和帕金森病中双重任务步行效应之间的关联.
- 检查执行功能,临床和社会人口统计学变量与PD中双重任务步行效应之间的关系.
- 为了确定生命前的因素是否会影响在PD中应对复杂的步态情况.
主要方法:
- 这是一项涉及44名患有帕金森病的参与者的横截面研究.
- 评估双重任务对步行参数的影响:节奏,脚步长度和步行速度.
- 与认知储备 (CRIq),执行功能 (TMT),全球认知 (MoCA,MMSE),年龄,性别和疾病严重程度的相关性分析.
主要成果:
- 认知储备在双重任务条件下没有显著影响步行表现.
- 执行功能,年龄和疾病严重程度与双重任务步行效应有关.
- 在Trail Making测试中,执行职能表现与双任务步态对节奏的影响呈反向关系.
结论:
- 认知储备的测量并没有减轻PD样本中的双重任务步行障碍.
- 执行职能,年龄和疾病严重程度是影响帕金森病步态复杂性的关键因素.
- 像教育这样的生命前因素似乎没有增强在PD中管理复杂步态情况的能力.
相关概念视频
Parkinson's Disease: Overview
512
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
512
Parkinson's Disease: Treatment
244
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
244


