垂直残留缺陷:疾病进展风险,再治疗率和成本:回顾性分析
Muhammad H A Saleh1, Dhiraj Mallala2, Abdusalam Alrmali2,3
1Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, 1011 North University Avenue, Ann Arbor, MI, 48109-1078, USA. muhsaleh@umich.edu.
Clinical oral investigations
|July 25, 2024
概括
放射性残留垂直缺陷 (RVDs) 增加了牙周维持治疗期间牙损失和口袋开口的风险. 患有RVD的患者需要更密切的监测,特别是那些患有糖尿病等危险因素的患者.
科学领域:
- 牙周病学 牙周病学
- 牙科成像 牙科成像 牙科成像
- 牙周维护疗法 牙周维护疗法
背景情况:
- 放射性残留垂直缺陷 (RVDs) 是接受牙周维持疗法 (PMT) 的患者的常见发现.
- 牙周炎对牙周炎进展和牙损失的长期影响仍然是积极研究的领域.
研究的目的:
- 在接受PMT的患者中调查RVD和牙周炎进展之间的关联.
- 为了确定加剧牙周炎进展的危险因素,牙与RVDs.
主要方法:
- 采用了一项比较性研究设计,分析相同患者中具有RVDs的牙与相反的牙.
- 评估的关键参数包括探测深度 (PD) 的减少,口袋关闭 (PC),牙周炎 (TLP) 的牙损失以及需要重新治疗的需要.
- 统计分析包括概括估计方程和回归模型,以评估RVD和各种风险因素的影响.
主要成果:
- 牙有RVDs在随访时显著减少了口袋关闭 (PC) 的患病率 (OR=0.5,p=0.028) 和因牙周炎而导致牙损失的风险翻了一番 (OR=2.28,p=0.043).
- 糖尿病,第四阶段牙周炎,牙移动性更高,牙周风险得分升高 (PRS) 是患有RVDs的患者牙损失的显著预测因素.
- 虽然重新治疗的发生率相似,但有RVD的牙的治疗费用高出30%,C级牙周炎是重新治疗的强有力的预测因素 (OR=18.8,p=0.005).
结论:
- 在牙周维护期间,RVD是牙损失和口袋开放增加的重要风险指标.
- 密切监测RVD患者,特别是具有全身 (如糖尿病) 和局部风险因素的患者,对于预防牙脱落至关重要.
- 与RVD相关的更高的再处理成本需要仔细考虑处理策略,包括提取和更换与长期维护.
相关概念视频
Actuarial Approach
71
The actuarial approach, a statistical method originally developed for life insurance risk assessment, is widely used to calculate survival rates in clinical and population studies. This method accounts for participants lost to follow-up or those who die from causes unrelated to the study, ensuring a more accurate representation of survival probabilities.
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
Consider the example of a high-risk surgical procedure with significant early-stage mortality. A two-year clinical study is conducted,...
71
Assumptions of Survival Analysis
119
Survival models analyze the time until one or more events occur, such as death in biological organisms or failure in mechanical systems. These models are widely used across fields like medicine, biology, engineering, and public health to study time-to-event phenomena. To ensure accurate results, survival analysis relies on key assumptions and careful study design.
119
Cancer Survival Analysis
336
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
336
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
125
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
125
Comparing the Survival Analysis of Two or More Groups
170
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
170
Introduction To Survival Analysis
203
Survival analysis is a statistical method used to study time-to-event data, where the "event" might represent outcomes like death, disease relapse, system failure, or recovery. A unique feature of survival data is censoring, which occurs when the event of interest has not been observed for some individuals during the study period. This requires specialized techniques to handle incomplete data effectively.
The primary goal of survival analysis is to estimate survival time—the time...
The primary goal of survival analysis is to estimate survival time—the time...
203


