在接受血造细胞移植的患者心血管方面的考虑
Jasmin Hundal1, Thomas Curley1, Betty K Hamilton2
1Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Current treatment options in oncology
|July 25, 2024
概括
血造细胞移植 (HCT) 可能导致心脏功能障碍,影响癌症患者的生存率. 本综述详细介绍了与HCT相关的心血管事件,风险因素和管理策略,以改善幸存者的结果.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 血液学 血液学 血液学
背景情况:
- 癌症疗法,包括造血细胞移植 (HCT),对心脏功能障碍构成重大风险.
- 心血管毒性是HCT接受者患病和死亡的主要原因.
- 这些毒性影响癌症患者的生活质量和长期生存.
研究的目的:
- 综合审查与HCT相关的心血管事件.
- 识别短期和长期心血管毒性的风险因素.
- 讨论目前对心血管风险评估的方法,并突出研究差距.
主要方法:
- 这是一个复习文章.
- 它综合了有关HCT后心血管并发症的现有文献.
- 它侧重于风险因素,临床表现和管理策略.
主要成果:
- 心血管事件可以在任何阶段发生:在HCT之前,期间和之后.
- 各种风险因素导致HCT患者的急性和慢性心脏问题.
- 目前的风险分层和评估方法需要进一步改进.
结论:
- 了解HCT相关的心血管事件对于改善患者护理至关重要.
- 识别和减轻心血管风险可以提高移植幸存者的长期生存率和生活质量.
- 需要进一步的研究来开发用于管理晚期心血管影响的新型干预措施.
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