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Updated: Jun 19, 2025

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快速诱导的酵母表面显示器用于用OrthoRep进行抗体进化

Alexandra M Paulk1,2,3, Rory L Williams2,3, Chang C Liu2,3,4,5

  • 1Program in Mathematical, Computational and Systems Biology, University of California, Irvine, California 92697, United States.

ACS synthetic biology
|July 25, 2024
PubMed
概括

我们改进了自主超变酵母表面显示 (AHEAD) 技术,以实现更快的抗体进化. 一种新的合成雌激素诱导系统显著加快了酵母细胞上的抗体显示,加速了抗体的发现.

关键词:
在OrthoRep中,可以使用OrthoRep.抗体工程是针对抗体的工程.过度突变是一种超级突变.纳米体是一个纳米体.酵母表面显示器显示酵母表面.

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