Pitx2和Tfap2a/Tfap2b的转录程序控制了牙启动期间下上皮质的谱系规范

Fan Shao1,2, An-Vi Phan1, Wenjie Yu3

  • 1Iowa Institute for Oral Health Research, University of Iowa College of Dentistry and Dental Clinics, Iowa City, Iowa, United States of America.

PLoS genetics
|July 25, 2024
PubMed
概括

研究人员确定了控制部发育的关键转录因子 (TFs). 破坏这些TF改变了牙的形成,揭示了脊椎动物下巴和牙开始部位的模式所必不可少的交叉抑制机制.

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