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由ACKR2缺乏NK细胞增强的CCR2表达增加了瘤杀伤细胞治疗的疗效

Alan J Hayes1, Marieke Pingen1, Gillian Wilson1

  • 1Chemokine Research Group, School of Infection and Immunity, College of Medical, Veterinary and Life Sciences, University of Glasgow, Sir Graeme Davis Building, 120 University Place, Glasgow G12 8TA, United Kingdom.

Journal of leukocyte biology
|July 25, 2024
PubMed
概括

在小鼠中非典型的化学因受体2 (ACKR2) 缺陷不会直接抑制转移. 增强的自然杀手细胞归因于突变,这表明CCR2+自然杀手细胞可以改善抗转移疗法.

关键词:
非典型的化学因受体转移 转移 转移 转移乘客的突变 乘客的突变

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