在多发性硬化症中出现抑郁症的最佳实践练习:系统性审查和元分析
Kristiina Ahola1, Diana Dorstyn1, Nicole Prideaux1,2
1Faculty of Health and Medical Sciences, School of Psychology, The University of Adelaide, Adelaide, Australia.
Clinical rehabilitation
|July 25, 2024
概括
定期炼可以显著减少患有多发性硬化症 (MS) 的成年人的抑郁症状. 然而,在训练停止后,这些好处会减少,这凸显了持续体育活动和适合移动性有限的人士的定制计划的需要.
科学领域:
- 神经学 神经学
- 运动科学 运动科学
- 精神病学是一个精神病学.
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经疾病,通常与抑郁症有关.
- 抑郁症显著影响了MS患者的生活质量.
- 了解MS抑郁症的有效干预措施至关重要.
研究的目的:
- 评估教练主导运动对成年多发性硬化症患者抑郁症状的影响.
- 确定可能会缓解对MS抑郁症运动干预反应的因素.
主要方法:
- 从多个数据库 (科克兰图书馆,Embase,PEDro,PsycINFO,PubMed) 进行研究的系统审查和元分析,直到2024年4月.
- 包括22项研究,785名参与者被诊断患有复发性复发或进展性MS.
- 使用PEDro和TESTEX尺度评估研究质量;使用随机和混合效应模型计算Hedges的g效应大小.
主要成果:
- 导师带领的炼表明,核心抑郁症症状显著减少 (g = 0.52,P < 0.01).
- 这些积极影响在停止炼计划后没有持续 (g = -0.53,P ≤ 0.01).
- 有氧和非有氧运动都带来了显著的改善;具有更好的基线行走能力的个体显示出更大的益处 (P = 0.03).
结论:
- 定期炼有效地稳定了多发性硬化症患者的情绪.
- 通过解决与流动性,炼类型,交付和强度相关的障碍,可以优化炼的有效性.
- 持续参与体育活动是MS患者持续情绪改善的关键.
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