未来的随机对照试验水交换加盖与水交换结肠镜在未经设置的退伍军人
Felix W Leung1, Ramsey Cheung2, Shai Friedland2
1Veterans Affairs Greater Los Angeles Healthcare System, University of California at Los Angeles, Los Angeles, California, USA.
Gastrointestinal endoscopy
|July 25, 2024
概括
单独的水交换 (WE) 已经足够用于退伍军人未经镇静的结肠镜检查. 添加WE的盖子并没有显著降低插入疼痛,表明WE本身是有效的.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 疼痛管理 疼痛管理
背景情况:
- 已知水交换 (WE) 和帽子辅助结肠镜可减少未安静患者的插入疼痛.
- 该研究旨在将WE与WE帽子辅助结肠镜 (WECAC) 进行比较,以减少实时最大插入疼痛 (RTMIP).
研究的目的:
- 为了确定WE帽子辅助结肠镜 (WECAC) 是否优于单独的水交换 (WE) 在减少非静止结肠镜期间的实时最大插入疼痛 (RTMIP) 中.
- 评估影响RTMIP的患者特定因素.
主要方法:
- 一个随机的,盲目的研究,涉及280名未经过药的退伍军人,在三个美国退伍军人事务站点没有护送.
- 测量的主要结果是RTMIP,在结肠镜插入期间以0到10的比例评分.
主要成果:
- 在WECAC (2.9) 和WE (2.6) 之间没有发现平均RTMIP的显著差异.
- 在不同组之间,管输管率 (93%对94.2%) 和腺瘤检测率 (48.3%对55.1%) 相似.
- 特定于患者的因素,而不是添加上限,被确定为RTMIP的预测因素.
结论:
- 单独的水交换 (WE) 足以在未经安慰的退伍军人结肠镜检查期间控制疼痛.
- 添加WE的盖子不会进一步减少插入疼痛.
- 优化WE技术和患者选择 (低焦虑,适当的BMI,没有抑郁症/健康状况不佳的病史) 可以最大限度地减少RTMIP.
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