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Updated: May 12, 2026

Functional Evaluation of Biological Neurotoxins in Networked Cultures of Stem Cell-derived Central Nervous System Neurons
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一个全面的协议,以有效地分化人类的NPC到电能神经元

Elena Romito1, Ingrid Battistella2, Vera Plakhova3

  • 1Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Via Fratelli Cervi, 93, Segrate, Milan 20054, Italy.

Journal of neuroscience methods
|July 25, 2024
PubMed
概括

这项研究提出了一个详细的协议,用于将人类诱导的多能干细胞分化为可靠的,电活跃的神经元. 该方法确保可复制的结果用于研究神经发育和疾病模型在体外.

关键词:
在体外培养人类神经元培养.诱导的多能干细胞干细胞神经前代细胞是神经前代细胞.神经元激活的过程神经元分化的不同.

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Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...