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Updated: Jun 19, 2025

Measuring DNA Damage and Repair in Mouse Splenocytes After Chronic In Vivo Exposure to Very Low Doses of Beta- and Gamma-Radiation
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耐受性值是胚胎发育过程中对DNA损伤的反应的基础

Gloria Jansen1,2, Daniel Gebert1,2, Tharini Ravindra Kumar1

  • 1Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.

Genes & development
|July 25, 2024
PubMed
概括

胚胎细胞通过发展抗性值,意外地耐受了可转移元素 (TE) 造成的DNA损伤. 这保护了在生殖线发育期间的基因组完整性,即使有显著的DNA双链断裂 (DSBs).

关键词:
克里斯普尔卡斯9造成的DNA损伤是DNA损伤.这种植物是Drosophila melanogaster.这就是P元素.双链断裂断裂的方法基因组的完整性 基因组的完整性发育的生殖线发展.混合动力异构的产生.介质变化 (meiosis) 是一种变质的过程.可转移的元素可以转移.

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