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Updated: Jun 19, 2025

Single-Molecule FRET Imaging for Observing the Conformational Dynamics of Dynamin-Like GTPase Atlastin
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Published on: January 24, 2025

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UNC-45辅助髓折叠取决于一个被保留的FX3HY动机,该动机与弗里曼·谢尔登综合征有关

Antonia Vogel1, Renato Arnese1, Ricardo M Gudino Carrillo1,2

  • 1Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria.

Nature communications
|July 25, 2024
PubMed
概括

UNC-45护卫器对于肌肉蛋白质量控制至关重要,确保了蛋白质的正确折叠和功能. 在这个过程中发生的干扰,特别是在FX3HY基因上,会导致肌蛋白聚合,并导致人体肌肉病变.

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