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在血液透析水中的潜在致病菌培养细菌

Shokouh Ghafari¹, Seyed Mohammad Alavi², Soheila Khaghani³

¹Cellular and Molecular Research Center, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.

BMC microbiology

|July 25, 2024

概括

对血液透析水系统的微生物学监测至关重要. 这项研究发现了潜在的危险细菌,如Sphingomonas,尽管内毒素水平仍然很低,这表明需要继续对水安全保持警,以保护患者的健康.

科学领域:

微生物学微生物学
环境健康环境健康
感染控制感染控制

背景情况:

血液透析患者容易患上与医疗保健相关的感染,原因是用于透析液制备的非无菌水.
微生物控制和血液透析中使用的水的监测对于患者的安全至关重要.

研究的目的:

为了在六个月的时间内识别血液透析水分配系统内的细菌种群.
评估血液透析水中发现的细菌所带来的潜在健康风险.

主要方法:

从血液透析水分配系统的三个点收集了18个样本.
使用R2A agar进行细菌计数和16S rRNA基因测序进行细菌识别.
使用Endosafe®快速LAL单测试瓶测量内毒素度.

主要成果:

鉴定出多样化的细菌群落,主要是格拉姆阴性细菌,其中斯芬戈蒙纳斯是最常见的属.
隔离了五种真菌细菌,包括M. fortuitum,M. lentiflavum,M. szulgai,M. barrassiae和M. gordonae. 这些细菌都被发现了.
尽管存在细菌,但所有样本都显示内毒素值低于检测极限.

结论:

斯芬哥马纳斯,波塞亚和菌根菌被确定为系统内生物膜形成的潜在先驱.
诸如Pelomonas,Bradyrhizobium,Staphylococcus和Microbacterium等细菌可能对血液透析患者构成健康风险.
持续监测对于减轻血液透析水系统中的感染风险至关重要.

关键词:

细菌细菌是一种细菌.生物膜是一种生物膜.血液透析水是为了血液透析.在NTM中,NTM是NTM.

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