甘油三糖指数 (TyG) 与中国正常体重成年人中风险之间的关联:一个基于人口的研究
Man Wu1,2, Chaoyang Li2,3, Yiqing Yu2
1Chengdu Third People's Hospital, Chengdu, China.
Diabetology & metabolic syndrome
|July 25, 2024
概括
三甘油糖 (TyG) 指数与正常体重的成年人中风风险增加有关. 这一发现表明,TyG指数可以帮助识别患中风风险较高的人.
科学领域:
- 心血管流行病学心血管流行病学
- 代谢综合征研究研究
- 关于预防中风的研究.
背景情况:
- 识别中风风险因素对于预防至关重要.
- 三甘油糖 (TyG) 指数是胰岛素抵抗的指标,可能与中风风险有关.
- 关于TyG指数和中风风险的现有证据不一致,需要进一步调查.
研究的目的:
- 评估TyG指数与中风风险水平之间的关联.
- 专门研究正常体重个体的这种关联.
主要方法:
- 分析了30895名正常体重的中国成年人 (体重指数18.5-23.9公斤/米2),年龄≥40岁.
- 该TyG指数是使用禁食甘油三和葡萄糖水平计算的.
- 使用中风风险评估尺度评估中风风险,并采用多变量逻辑回归模型来评估中风风险.
主要成果:
- 较高的TyG指数水平与中度和高风险的增加显著相关.
- 与最低四分位数 (Q1) 相比,TyG指数的最高四分位数 (Q4) 中的个体中风风险中适度和高的几率要高得多.
- 在代谢肥胖,正常体重 (MONW) 个体中,TyG指数是高中风险的重要风险因素.
结论:
- 三糖糖 (TyG) 指数与正常体重的中国成年人中风风险增加有关.
- 泰格指数可以作为一种有价值的工具,用于识别那些有正常体重且患中风风险较高的人.
- 这些发现支持TyG指数在正常体重人群中卒中预防策略中的潜在作用.
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