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Updated: Jun 19, 2025

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在患有原发性免疫性血小板缩症的儿童中,介质素 (IL) - 1B和IL-1受体对手基因多态

Seham Mohamed Ragab1, Wafaa Moustafa Abo ElFotoh1, Mahmoud Ahmed El-Hawy1

  • 1Pediatrics Department, Faculty of medicine, Menoufia University, Shebin Elkom, Menoufia, Egypt.

Clinical and experimental pediatrics
|July 26, 2024
PubMed
概括

干白素-1B (IL-1B) 和干白素-1受体对抗剂 (IL-1RA) 基因的遗传变异与儿童初级免疫血栓缩 (ITP) 易感性有关. 特定的IL-1B和IL-1RA基因多态性显著增加了儿童患ITP的风险.

关键词:
孩子孩子孩子孩子孩子孩子基因多形态的多态化介质蛋白是介质蛋白中的一种.主要免疫性血小板缺血症.

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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