接种SARS-CoV-2疫苗可以改善从COVID-19中恢复过来的男性的精液质量:一项回顾性队列研究
Yuanqi Zhao1,2, Yangyang Wan1, Xuechun Hu3
1Center for Reproduction and Genetics, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, P.R. China.
American journal of men's health
|July 26, 2024
概括
从SARS-CoV-2感染中康复的男性接种COVID-19疫苗显示精液质量暂时下降. 随着时间的推移,精液参数得到了改善,无活化疫苗增强剂增强了精子的运动性和数量.
科学领域:
- 生殖医学 生殖医学
- 传染性疾病 传染性疾病
- 疫苗学 疫苗学 疫苗学
背景情况:
- 以前的报道表明,新冠病毒病2019 (COVID-19) 对男性精液质量产生了负面影响.
- 疫苗接种男性的SARS-CoV-2感染对精液参数的影响需要进一步调查.
研究的目的:
- 评估COVID-19康复和疫苗接种对生殖年龄男性精液质量的影响.
- 为了比较不同类型的疫苗 (无活化与重组蛋白) 和助推剂对感染后的精液参数的影响.
主要方法:
- 招募了1639名接受COVID-19疫苗接种的生殖年龄的中国男性.
- 精子参数包括精子度,运动性和形态学,这些参数在COVID-19后的时间恢复后被分析.
- 在接受了无活化疫苗增剂,重组蛋白质疫苗或在SARS-CoV-2感染后没有增剂的男性之间进行了比较.
主要成果:
- 在COVID-19康复和接种疫苗后,在精子度,渐进性运动性,总运动性,总运动性精子数 (TMSC) 和随着时间的推移的正常形态学中观察到显著的上升趋势.
- 与没有助推剂的男性相比,持有持续不到30天的SARS-CoV-2感染的男性,接受了无活化疫苗增剂,表现出精子进展性运动性,总运动性和TMSC的改善.
- 较高的精子和精子的风险与持续不到30天的SARS-CoV-2感染有关.
结论:
- 在接种疫苗的男性中,SARS-CoV-2感染后的不良精液参数是暂时的和可逆的.
- 再组合蛋白质疫苗和无活化疫苗增强剂在从COVID-19中恢复过来的男性中显示出对生殖健康的潜在益处.
- 对所有生殖年龄的男性建议使用复合蛋白疫苗和非活化疫苗增强剂.
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