相关实验视频

Updated: Jun 19, 2025

Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster
10:26

Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster

Published on: March 12, 2018

8.0K

单细胞的柔软玻璃状风湿学与致病性蛋白质聚合物

Shatruhan Singh Rajput1,2, Surya Bansi Singh3,4, Deepa Subramanyam3

  • 1Department of Physics, Indian Institute of Science Education and Research, Pune 411008, India.

Soft matter
|July 26, 2024
PubMed
概括

细胞机械特性,特别是粘性弹性,随着疾病而变化. 致病性蛋白质聚合物可以使细胞更像固体,影响细胞运输和行动组织,但这种情况可以逆转.

更多相关视频

A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model08:24

A Method to Study α-Synuclein Toxicity and Aggregation Using a Humanized Yeast Model

Published on: November 25, 2022

2.2K
Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation09:16

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

Published on: June 26, 2018

7.5K

相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
9.5K