在COVID-19后六个月的胸部CT发现 ARDS - 与mMRC呼吸障碍量表和肺功能测试的相关性
Mandeep Garg1, Nidhi Prabhakar1, Shritik Devkota1
1Department of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
British journal of biomedical science
|July 26, 2024
概括
患有严重的COVID-19急性呼吸困扰综合征 (ARDS) 和持续呼吸问题的幸存者在康复六个月后显示特定的肺部CT扫描模式与他们的呼吸困难和肺功能减弱有关.
科学领域:
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 严重的COVID-19肺炎幸存者经常面临持久的呼吸系统问题.
- 在COVID-19 ARDS患者的长期胸部成像发现中,关于呼吸障碍和肺功能的研究有限.
研究的目的:
- 为了调查临床特征,修改了医学研究委员会 (mMRC) 呼吸障碍得分,肺功能测试 (PFT) 和胸部计算机断层扫描 (CT) 在COVID-19 ARDS患者的发现,在康复后六个月.
- 通过分析这些变量来了解COVID-19 ARDS对健康的长期影响.
主要方法:
- 一项针对56名COVID-19 ARDS患者的前性观察性研究,在六个月的随访期间患有呼吸障碍.
- 评估包括胸部CT,mMRC呼吸障碍量表和PFTs.
- 一个经过修改的CT严重性评分系统评估了地面玻璃不透明度 (GGOs),膜/无膜带,网膜/septal加厚和巩固;统计分析探索了与mMRC和强迫生命能力 (FVC) 的关联.
主要成果:
- 该研究包括56名患者 (平均年龄为55.86岁,78.6%是男性).
- 常见的CT检测结果是GGO (94.6%),网膜/隔膜加厚 (96.4%),以及膜/无膜带 (92.8%).
- 网膜/横膜加厚 (p=0.0129) 和对体/无体带 (p=0.0453) 与增加的mMRC得分相关;对体/无体带也与减少的FVC相关 (p=0.0233).
结论:
- 在COVID-19 ARDS幸存者患有呼吸系统问题的六个月后续胸部CT显示出呼吸困难严重程度和特定成像模式之间的重要联系.
- 电脑图谱上的网膜/septal 加厚和 parenchymal/atelectatic 带与较高的mMRC 评分有关.
- 帕伦基马/无带与强迫生命能力 (FVC) 的降低特别相关.
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