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人类的一天的直径 五个胚胎细胞和出生性别
Ensar Hajder1, Cornelius Doehmen2, Jan-Steffen Kruessel1
1Reproductive Medicine, University Clinic Dusseldorf, Dusseldorf, DEU.
Cureus
|July 26, 2024
概括
这项研究发现,单个胚胎细胞移植后,更多的雌性后代倾向于产生雌性后代. 在辅助生殖技术周期中,胚胎细胞直径与后代的性别没有明显的相关性.
科学领域:
- 生殖医学 生殖医学
- 胚胎学 胚胎学
- 遗传学 是一个遗传学.
背景情况:
- 辅助生殖技术 (ART) 涉及到实现怀孕的复杂程序.
- 胚胎囊 (BL) 形态是用于单个胚胎移植 (SET) 的胚胎选择的关键因素.
- 囊胚形态与后代性别比率之间的关系需要进一步研究.
研究的目的:
- 为了评估新鲜和冷解单个胚胎细胞移植后的后代的性别比.
- 评估胚芽细胞直径和产生的后代的性别之间的相关性.
- 为了比较新鲜胚胎转移和冷胚胎转移的胚胎直径,以及体外受精 (IVF) 和细胞内精子注射 (ICSI) 周期之间的胚胎转移.
主要方法:
- 在ART中心进行了回顾性观察性研究.
- 在SET之后,对新鲜和解的IVF/ICSI周期的出生进行统计分析.
- 主要结果指标:后代的性别比率与第五天的胚胎囊径相比.
主要成果:
- 出生的女婴比男婴的比例更高.
- 在导致雌性后代的病例中,观察到更大的胚胎细胞直径的非统计学意义上的趋势.
- 新鲜胚胎移植与冷解移植相比,显示出更大的胚胎囊径的趋势.
- ICSI周期往往比试管婴儿周期更大的胚胎囊径.
- 在新鲜转移周期和冷解转移周期之间,发现了与后代性别相对的胚胎细胞直径的矛盾趋势.
结论:
- 在单个胚胎囊移植后,观察到女性后代性别比率的趋势.
- 在ART后导致分娩的胚胎囊中,没有发现胚胎囊直径的显著差异.
- 囊胞直径可能不是SET结果中后代性别的可靠预测指标.
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