受试管婴儿治疗的夫妇的焦虑:来自E-Freeze随机对照试验的证据
Yangmei Li1, Jenny McLeish1, Pollyanna Hardy1
1National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Human reproduction open
|July 26, 2024
概括
接受试管婴儿的妇女的焦虑受不孕持续时间,种族和伴侣焦虑的影响. 然而,女性的焦虑程度不会影响试管婴儿试验中的临床怀孕率.
科学领域:
- 生殖医学 生殖医学
- 在生育治疗中的心理健康.
- 在辅助生殖的临床试验.
背景情况:
- 体外受精 (IVF) 的使用正在增加,患者经历了显著的焦虑.
- 参加随机对照试验 (RCT) 和延迟治疗可能会加剧患者的焦虑.
研究的目的:
- 在一项随机试验中,对异性恋夫妇接受试管婴儿试管婴儿的风险因素和焦虑的影响进行调查.
- 检查与治疗手臂分配有关的焦虑,特别是胚胎移植的延迟.
主要方法:
- 一项混合方法研究分析了604对夫妇在多中心E-FreezeRCT (英国,2016-2019年) 中的数据.
- 在同意 (T1) 和胚胎移植 (T2) 时,测量了国家和地区焦虑清单 (STAI-S) 评分.
- 回归分析探讨了焦虑得分与人口统计学/临床因素之间的关联,并进行了问卷的定性内容分析.
主要成果:
- 妇女在T1的焦虑与不孕症的持续时间,种族和男性伴侣的焦虑有关. 在T2时,女性的焦虑与种族,诊所位置,自己的T1得分和伴侣的T2得分相关.
- 女性报告的焦虑率高于男性,在T1和T2之间增加更大.
- 最重要的是,女性的焦虑评分与不遵守或临床怀孕率无关.
结论:
- 试管婴儿患者的焦虑受到各种因素的影响,包括伴侣焦虑和人口统计特征.
- 妇女可以放心地说,她们自我报告的焦虑不会影响试管婴儿成功 (临床怀孕).
- 以患者为中心的护理,明确的沟通和工作人员的支持对于在试管婴儿期间管理心理健康至关重要.
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