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随机对照试验在青少年跨性别者医疗保健中在方法上不合适

Florence Ashley¹, Diana M Tordoff², Johanna Olson-Kennedy^3,4

¹Faculty of Law & Joint Centre for Bioethics, University of Toronto, Toronto, ON, Canada.

International journal of transgender health

|July 26, 2024

概括

随机对照试验 (RCT) 不适合研究青少年性别肯定护理. 精心设计的观察性研究为临床实践和政策提供了可靠的证据,支持跨性别年轻人的心理健康结果.

科学领域:

医学伦理学医学伦理学
青少年健康青少年健康
心理健康研究心理健康研究

背景情况:

观察性研究将肯定性别的护理与青少年的积极心理健康联系起来.
由于缺乏随机对照试验 (RCT),一些地区限制了未成年人的医疗干预.

研究的目的:

批判性地评估RCT在研究青少年性别确认护理和心理健康方面的方法性适当性.
确定是否需要RCT来验证性别肯定干预措施对心理健康的益处.

主要方法:

对科学文献进行批判性审查.
在性别肯定护理的背景下,分析RCT的方法限制.
评估观察性研究对这一研究领域的适用性.

主要成果:

在评估跨性别青少年性别肯定护理对心理健康的影响方面,RCT的科学价值极为有限.
生理效应和参与者对干预的渴望引起了人们对RCT的坚持,退出和偏见的担忧.
精心设计的观察性研究更合适,并提供可靠的证据.

结论:

没有RCT并不意味着性别肯定干预措施的证据不足.
风险试验的方法限制使得观察性研究成为更可靠的证据来源.
观察性研究足以指导青少年跨性别者医疗保健的临床实践和政策.

关键词:

基于证据的医学是基于证据的医学.肯定性别的护理.随机对照试验是随机对照试验.研究方法研究方法.变性人是指变性人,是指变性人.

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