构建和评估在重症监护病房中使用机械通风的患者中获得的弱点诺莫格拉姆模型
1Jiangsu Taizhou People's Hospital, Taizhou, China.
Digital health
|July 26, 2024
概括
鉴定了重症监护病房获得衰弱 (ICU-AW) 风险因素,如机械通风持续时间,APACHE II,SOFA分数,年龄,神经阻塞剂和糖尿病等. 一个预测性名录显示了早期ICU-AW风险评估的强效.
科学领域:
- 关键护理医学 关键护理医学
- 神经学 神经学
- 老年病的医生 老年病的医生
背景情况:
- 重症监护室获得的虚弱 (ICU-AW) 是一个越来越严重的问题,治疗选择有限.
- 早期识别患有ICU-AW风险的患者对于及时干预至关重要.
研究的目的:
- 在机械通风患者中确定ICU-AW的独立风险因素.
- 开发和验证一个用于预测ICU-AW风险的名录图.
主要方法:
- 机械呼吸患者的观察研究 (2020年1月 - 2023年1月).
- 多变量物流回归分析以确定风险因素.
- 使用培训和验证队伍构建和验证nomogram.
主要成果:
- 机械通风的持续时间,APACHE II分数,SOFA分数,年龄,神经阻断剂和糖尿病都是重要的危险因素.
- 在训练 (AUC=0.950) 和验证 (AUC=0.823) 队列中,名图显示出高预测效率.
结论:
- 机械通风持续时间,APACHE II,SOFA,年龄,神经阻断剂和糖尿病是ICU-AW的关键预测因素.
- 开发的诺米图有效预测了ICU-AW风险,并可能有助于临床决策.
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