在埃塞俄比亚的2型糖尿病患者中,失控高血压的预测因素:多中心截面研究
Leteslase Hagos Gebreziher1, Melak Gedamu Beyene2, Desalew Mekonnen3
1Adigrat University, College of Medicine and Health Sciences, Department of Pharmacy, PO Box 50, Adigrat, Ethiopia.
概括
在2型糖尿病患者中,不受控制的高血压是常见的,特别是在年轻人中,那些药物坚持不良的人,肥胖者和不受控制的血糖. 改善生活方式因素和坚持是控制血压的关键.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 高血压 (HTN) 是2型糖尿病 (T2DM) 的常见并发症.
- 无法控制的HTN显著增加各种健康并发症的风险.
- 这项研究调查了T2DM患者中不受控制的HTN的患病率和预测因素.
研究的目的:
- 为了确定T2DM患者中不受控制的高血压的程度.
- 在这个人群中确定与不受控制的高血压相关的关键预测因素.
主要方法:
- 进行了一项多中心,横截面的研究.
- 从2021年9月19日至2021年12月17日期间的高血压T2DM患者收集了数据.
- 后勤回归分析被用来识别失控血压 (血压≥130/80 mmHg) 的预测因素.
主要成果:
- 在400名参与者中,只有39%的人达到目标血压.
- 无法控制的HTN的预测因素包括年龄较小,不坚持药物治疗 (OR=2.0),饮食盐摄入量减少 (OR=2.4),无法控制的血糖 (OR=2.4),肥胖 (OR=3.2),以及不经常的随访 (OR=2.3).
- 对于不遵守,食盐,血糖控制,肥胖和随访频率观察到的统计学意义.
结论:
- 在高血压的T2DM患者中,达到目标血压的水平低于最佳水平.
- 较年轻的患者,那些不坚持药物治疗,饮食盐摄入量高,肥胖,随访不频繁,血糖控制不佳的患者有更高的风险不受控制的HTN.
- 专注于药物坚持,减少食盐,定期随访和血糖控制的干预措施对于管理T2DM中HTN至关重要.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.3K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.3K
Hypertension and Regulation of Blood Pressure
2.0K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
2.0K
Diabetes: Symptoms, Diagnosis, and Complications
521
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
521
Diabetes Mellitus: Overview and Type I Subtype
2.5K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.5K
Carbohydrate Metabolism
10.9K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.9K
Diabetes: Management and Pharmacotherapy
256
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
256


