心血管疾病增加成人癌症死亡率:NHANES持续研究
Omar M Makram1,2, Tochukwu Okwuosa3, Daniel Addison4
1Department of Medicine Medical College of Georgia at Augusta University Augusta GA USA.
Journal of the American Heart Association
|July 26, 2024
概括
心血管疾病 (CVD) 增加了癌症死亡风险. 肥胖加剧了这种风险,强调需要管理共同的风险因素,以获得更好的健康结果.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 在瘤学瘤学.
背景情况:
- 癌症和心血管疾病 (CVD) 是全球主要的死亡原因.
- 关于心血管疾病,其风险因素和癌症死亡率之间的关系的证据有限.
研究的目的:
- 调查心血管疾病 (CVD) 与癌症死亡率之间的关联.
- 检查心血管风险因素在癌症死亡率中的作用.
主要方法:
- 使用NHANES (国家健康和营养检查调查),医疗保险和国家死亡指数数据 (1999-2018) 的前性队列研究.
- 包括44,591名没有癌症病史的成年人,分析心血管疾病作为主要暴露和风险因素作为次要.
- 采用竞争性风险建模来评估癌症死亡率结果.
主要成果:
- 患有心血管疾病的人患癌症死亡率的风险显著增加 (aHR, 1.37).
- 癌症死亡风险随着年龄,目前的吸烟和肥胖而增加.
- 显著的相互作用显示,心血管疾病和肥胖症患者的癌症死亡率更高 (aHR, 1.73).
结论:
- 心血管健康和癌症死亡率之间存在着强烈的联系.
- 肥胖在患有心血管疾病的个体中显著导致癌症死亡率.
- 积极管理心血管疾病和癌症的共同风险因素至关重要.
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