性别对死亡率的不同影响根据年龄在心力衰竭中的不同影响
Yoonpyo Lee1,2, Minjae Yoon1, Dong-Ju Choi1
1Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital Seoul National University College of Medicine Seongnam Republic of Korea.
Journal of the American Heart Association
|July 26, 2024
概括
在急性心力衰竭患者中,男性性别独立地预测了老年人的死亡率更高,但不是年轻人. 这种年龄差异突显了心力衰竭结果的关键差异.
科学领域:
- 心脏病学 心脏病学
- 老年病的医生 老年病的医生
- 基于性别的医学是基于性别的.
背景情况:
- 建立了基于性别的心力衰竭患病率,特征和结果的差异.
- 在急性心力衰竭 (AHF) 中,基于性别的差异和年龄之间的相互作用仍然不太清楚.
- 这项研究解决了亚洲患者住院治疗AHF的与年龄相关的性别差异.
研究的目的:
- 为了研究急性心力衰竭住院的亚洲患者在治疗结果中的基于性别的差异.
- 为了确定这些基于性别的差异是否因患者年龄而改变.
- 确定急性心力衰竭死亡率的特定年龄预测因素.
主要方法:
- 来自两个韩国注册局 (KorHF和KorAHF) 的数据汇总了8825名因急性心力衰竭住院的患者.
- 患者被分为两个年龄组:<70岁和≥70岁.
- 根据性别和年龄组分析了住院和出院后的死亡率,并对共变量进行了调整.
主要成果:
- 老年女性平均年龄大于老年男性.
- 在老年人群 (≥70岁) 中,基线特征在性别之间有显著差异.
- 住院和出院后的死亡率在男性中明显高于女性,仅在老年人群 (≥70岁) 中,在调整后仍然存在.
结论:
- 男性性别是急性心力衰竭的老年患者死亡率增加的独立预测因素.
- 在较年轻的患者 (70岁以下) 中,没有观察到基于性别的显著死亡率差异.
- 年龄是改变性对急性心力衰竭结果影响的关键因素.
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