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作为DGBI症状严重程度的修饰者,COVID-19大流行:系统性审查和元分析

Dmitrii Kulin^1,2,3, Ayesha Shah^1,2,3, Thomas Fairlie^1,2,3

¹Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

Neurogastroenterology and motility

|July 26, 2024

概括

在COVID-19大流行期间,许多患有肠-大脑相互作用障碍 (DGBI) 的患者经历了恶化的症状. 社会经济和政策因素影响了DGBI患者症状严重程度的变化.

科学领域:

胃肠病学胃肠病学
公共卫生公共卫生
流行病学流行病学

背景情况:

COVID-19 疫情对全球健康和日常生活产生了重大影响.
肠-大脑相互作用障碍 (DGBI) 是功能性胃肠道障碍,受肠-大脑轴通信的影响.
疫情期间生活方式和医疗保健准入的变化可能影响了DGBI症状的严重程度.

研究的目的:

在COVID-19大流行期间系统地审查和评估DGBI症状严重程度的变化.
评估各种社会人口统计,经济和政策相关因素对这些症状变化的影响.

主要方法:

系统审查和对2024年2月之前发表的研究进行元分析.
包括12项涉及3610名DGBI患者的研究.
综合分析症状严重程度的变化和基于国家一级因素的子组分析.

主要成果:

大约31.4%的DGBI患者报告症状恶化,而24.3%报告改善.
与较低GDP国家 (9.2%) 相比,较高GDP国家的症状恶化的可能性更高 (43.5%).
温和的COVID政策,低的COVID死亡率和高的疫苗犹与症状恶化的增加有关.

结论:

在DGBI患者中,很大一部分在COVID-19大流行期间经历了症状恶化.
社会文化,经济和环境因素在改变大流行对DGBI症状的影响方面发挥了作用.
需要进一步的研究来理解这些复杂的相互作用,并制定有针对性的干预措施.

关键词:

根据COVID-19的情况,总局DGBI 总局DGBI 总局肠-大脑相互作用的障碍.这是一个元分析.患病率的流行情况.症状严重程度症状严重程度

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