早期在激光修饰的表面上进行植入后的骨愈合,有或没有氧酸涂层:一个实验室研究
Ana Flávia Piquera Santos1, Rodrigo Capalbo da Silva2, Henrique Hadad1
1Department of Diagnosis and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, Brazil.
Biology
|July 26, 2024
概括
激光修饰的植入物表面,包括含有酸的植入物表面,与子骨中的标准加工表面相比,增强了骨组织沉积和植入物稳定性.
科学领域:
- 生物材料科学 生物材料科学
- 整形外科的研究研究.
- 表面工程是什么?表面工程是什么?
背景情况:
- 牙植入成功取决于骨质整合.
- 表面修改可以改善骨植入物相互作用.
- 评估新型表面处理对于改善临床结果至关重要.
研究的目的:
- 评估骨组织对加工表面 (MS) 的生物反应与激光修饰表面 (LS) 和用酸 (LHS) 激光修饰表面相比.
- 使用仿生方法比较不同植入物表面地形的骨质整合潜力.
- 评估表面修改对植入物生物力学稳定性和骨位置的影响.
主要方法:
- 使用扫描电子显微镜 (SEM) 和能量分散式X射线光谱 (EDX) 进行表面表征.
- 在子骨中进行了生物机械去除扭矩测试和组织学分析 (%BIC,%NBA).
- 使用共聚焦激光显微镜进行矿物质附加率评估.
主要成果:
- SEM揭示了MS,LS和LHS之间明显的表面形态差异.
- 2周后,LHS的移除扭矩明显高于MS;4周后,LS和LHS的移除扭矩高于MS.
- 在2周后,LHS表现出优异的骨与植入物接触 (%BIC),在4周后,LS和LHS都表现出优异.
- 在2周后,在LHS和MS之间观察到新形成的骨面积 (%NBA) 的显著差异.
结论:
- 激光表面修饰 (LS和LHS) 诱导了有利的物理化学变化.
- 这些修改促进了骨组织沉积和骨质整合的增强.
- 这项研究支持使用激光修饰的表面来提高牙植入物的性能.
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Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...