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Updated: Jun 19, 2025

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
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解决下部运动神经元损伤的新技术和在脊髓损伤中增强重建

Stanley F Bazarek1,2, Matthias J Krenn1,3,4,5, Sameer B Shah6,7

  • 1Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Cells
|July 26, 2024
PubMed
概括

在脊髓损伤 (SCI) 后的下部运动神经元 (LMN) 损伤导致肌肉退化. 这篇评论探讨了通过神经再生策略和电刺激来逆转这种缩,以改善功能.

关键词:
尾巴马的尾巴 (cauda equina) 是一个马的尾巴.细胞移植移植 细胞移植体中枢的体 (conus medullaris) 是一个缩性缩性缩性缩 (英语:denervation atrophy) 是一种致死性缩性缩.电刺激是一种电刺激.神经转移 神经转移 神经转移 神经转移干细胞疗法是一种干细胞疗法.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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