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新生儿角膜炎的流行率和物种分布:系统性审查和元分析
1Department of Medicine, College of Medicine, Taibah University, Madinah 42353, Saudi Arabia.
Diseases (Basel, Switzerland)
|July 26, 2024
概括
沙特阿拉伯的新生儿败血症病例中有4.2%是由Candida种类引起的,Candida albicans是最常见的. 由于数据有限,需要对风险因素和治疗进行进一步的研究.
科学领域:
- 医学微生物学 医学微生物学
- 新生儿科学 新生儿科学
- 传染性疾病 传染性疾病
背景情况:
- 全球新生儿候选性感染对新生儿重症监护室 (NICU) 的发病率和死亡率有重大影响.
- 了解Candida的流行和物种分布对于有效的管理至关重要.
研究的目的:
- 系统地审查Candida的流行率作为沙特阿拉伯新生儿败血症的原因.
- 确定该地区感染新生儿的Candida物种的分布.
主要方法:
- 从研究开始到2023年11月的综合系统审查和元分析.
- 搜索了包括Web of Science,Scopus,PubMed和Cochrane图书馆在内的数据库.
- 包括21项具有不同设计的研究,评估方法质量.
主要成果:
- 在沙特新生儿 (1823名婴儿) 中,Candida物种占新生儿败血症病例的4.2%.
- 主要的物种是Candida albicans (50.25%),其次是C. parapsilosis (21.40%),NS Candida (12.44%),以及C. tropicalis (9.45%). 在这些物种中,Candida albicans占主导地位.
- 从21项涉及2346名新生儿的研究中汇总了数据.
结论:
- 在沙特阿拉伯,Candida物种是新生儿败血症的重要原因之一,C. albicans是最常见的.
- 由于数据不足,无法分析风险因素和抗真菌敏感性.
- 建议在未来进行大规模,高质量的研究.
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