大动脉感染性内心炎由环状复杂化:在腔中使用抗生素
Zaki Haidari1, Shehla Ufaq Ahmad1, Stephan Knipp1
1Department of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center Essen, University Hospital Essen, 45147 Essen, Germany.
Journal of cardiovascular development and disease
|July 26, 2024
概括
局部抗生素没有显著影响大动脉内心炎与环状的结果. 激进脱bridement和补丁修复是有效的,但抗生素腔填充没有显示在预防复发或减少死亡率的好处.
科学领域:
- 心血管外科心血管外科
- 传染性疾病 传染性疾病
- 心脏外科手术 心脏外科手术
背景情况:
- 带有环状的大动脉感染性内心炎带来了手术挑战.
- 在腹脱bridement后,补丁重建通常是必要的.
- 建议使用局部抗生素,以防止内心炎复发.
研究的目的:
- 评估局部抗生素在患有由环状复杂的大动脉感染性内心炎的患者中的疗效.
- 为了比较接受和不接受局部抗生素的患者之间的结果.
主要方法:
- 在2012-2021年期间,对41名因有环状的大动脉内心炎接受心脏手术的患者进行了回顾性研究.
- 患者接受了激进的脱bridement和环状补丁重建.
- 对20名接受局部抗生素治疗的患者和21名不接受局部抗生素治疗的患者的结局进行比较.
主要成果:
- 在各组 (1个) 之间,复发性内心炎的发病率没有显著差异.
- 在各组之间,重新开放率相似.
- 局部抗生素组的两年死亡率为30%,对照组的24% (p=0.65).
结论:
- 激进脱bridement和补丁重建是对大动脉环状的有效手术策略.
- 在腔中使用局部抗生素并没有改变两年内复发性内心炎,再手术或死亡率.
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