生物假体与生物假体的年龄特定结果. 机械动脉替换:平衡重新操作风险与抗凝荷负担
Fatimah A Alhijab1, Latifa A Alfayez2, Essam Hassan1
1Adult Cardiac Surgery Department, Prince Sultan Cardiac Center, Riyadh 12233, Saudi Arabia.
Journal of cardiovascular development and disease
|July 26, 2024
概括
在50岁以上的患者中,生物假体和机械大动脉置换 (AVR) 的结果相似. 较年轻的患者 (<50岁) 生物假体AVR面临更高的再干预率,但不降低出血或中风风险.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 生物医学工程 生物医学工程
背景情况:
- 大动脉置换 (AVR) 假肢选择涉及平衡抗凝风险与重新干预需求.
- 这项研究调查了不同年龄组的生物假肢与机械AVR结果.
研究的目的:
- 为了比较生物假体和机械大动脉假体在根据年龄分层的患者 (≤50与>50岁) 的长期结果.
- 根据假肢类型和患者年龄来评估并发症风险,重新干预和生存率.
主要方法:
- 在2009年至2019年期间,对292名接受隔离AVR的成年患者进行了回顾性分析.
- 患者被分为四组:生物假体 (>50岁和≤50岁) 和机械 (>50岁和≤50岁).
- 包括重新手术,中风,出血和生存时间在内的结果在各组之间进行了比较.
主要成果:
- 在生物假肢和机械AVR之间没有观察到跨年龄组的生存率,中风或出血率的显著差异.
- 患有生物假体门的50岁以下的患者经历了显著更高的主动脉再干预率.
- 在接受机械AVR的50岁以上患者中,重新探索出血的频率更高.
结论:
- 在50岁以上的患者中,动脉置换的结果与生物假体和机械的结果相似.
- 在50岁以下的患者中,生物假体门与增加的重新干预率有关,而不会减轻出血或中风风险.
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