在雌激素期间,健康的处女马的阴道和子宫微生物群
Ana Gil-Miranda1, Benjamin Caddey2, Daniela Orellana-Guerrero3
1Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
Veterinary sciences
|July 26, 2024
概括
健康的少女马的子宫和阴道微生物群类似,但与阴蒂和周围皮肤不同. 这项研究描述了马类繁殖道和皮肤微生物群落在雌性期的特征.
科学领域:
- 兽医微生物学 兽医微生物学
- 马类生殖健康 马类生殖健康
- 微生物组研究 微生物组研究
背景情况:
- 生殖道微生物群在动物健康中起着至关重要的作用.
- 了解马的微生物群对于繁殖成功和疾病预防至关重要.
- 之前的研究还没有完全描述马匹生殖道和相关皮肤区域内的不同微生物群落.
研究的目的:
- 为了比较子宫,阴道,阴囊 (CF) 和健康的女马在雌激发期间的围皮肤的微生物群.
- 通过这些不同的解剖位置识别细菌组成的差异和相似之处.
- 描述马匹生殖道和皮肤中占主导地位的细菌种群.
主要方法:
- 描述性横截面研究,涉及十二只健康的处女马.
- 使用Illumina MiSeq平台进行16S rRNA基因测序 (V3-V4区域).
- 微生物丰富度 (Chao-1) 和组成 (Jaccard和Bray-Curtis距离) 的分析.
主要成果:
- 与皮肤微生物群相比,子宫和阴道微生物群的丰富性明显较低 (p < 0.05).
- 子宫和阴道的细菌组成与阴蒂和周围皮肤相似且不同.
- 微生物组成在各个身体部位上有显著差异,解释了14-19%的变化.
- 菌,动菌,蛋白菌和细菌群是占主导地位的种类;乳酸菌群显著低 (<10%).
结论:
- 在雌激发期间,健康的少女母马的子宫和阴道微生物群是相似的.
- 这些内部生殖道微生物群与阴茎和周围皮肤微生物群不同.
- 这项研究为马匹生殖系统中微生物群落的局部化提供了宝贵的见解.
相关概念视频
01:18Surface Membrane Barriers
1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
01:18Menses Phase
249
The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
249
01:19Secretory Phase
639
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
639