荷尔蒙和受到干扰:在间歇性肺部疾病中出现甲状腺功能低下和糖尿病. 一个观察性研究研究
Manju Bala1, Akhlesh Rajpoot2, Dinesh Chandra Punera3
1Department of Respiratory Medicine, Soban Singh Jeena Government Institute of Medical Science and Research, Almora, Uttarakhand. drmanju2015@gmail.com.
概括
与慢性阻塞性肺病 (COPD) 患者相比,间歇性肺病 (ILD) 患者患甲状腺功能低下症和糖尿病 (DM) 的患病率更高. 在ILD中查这些疾病对于更好的管理和结果至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 内分泌学 在内分泌学.
- 内部医学 内部医学
背景情况:
- 间歇性肺病 (ILD) 和慢性阻塞性肺病 (COPD) 是各种并发症的慢性呼吸道疾病.
- 在ILD和COPD患者中甲状腺功能低下症和糖尿病 (DM) 的关系和患病率尚不清楚.
- 了解这些并发症对于有效的患者管理和治疗策略至关重要.
研究的目的:
- 为了确定甲状腺功能低下症和糖尿病 (DM) 在患有间歇性肺部疾病 (ILD) 的患者的患病率.
- 为了比较ILD患者中的甲状腺功能低下和DM患病率与慢性阻塞性肺病 (COPD) 患者的患病率.
- 突出这些内分泌疾病的查在ILD患者中的重要性.
主要方法:
- 在北印度进行的一项横截面,前性观察性研究.
- 100名ILD患者和100名COPD患者从第三级护理医院的呼吸道医学门诊部注册.
- 收集了人口统计,临床和医疗数据,并进行了统计分析,以评估甲状腺功能低下症和DM的患病率.
主要成果:
- 与COPD患者 (p<0.05) 相比,ILD患者的甲状腺功能低下症 (24%对4%) 和DM (24%对4%) 的患病率明显高 (p<0.05).
- 在ILD患者中,自我报告的胃食道逆流性疾病的患病率也更高 (30%),BMI更高,并且更早地寻求肺科医生的咨询.
- 在ILD队列中,甲状腺功能低下症和DM患病率增加的统计学意义被观察到.
结论:
- 与COPD相比,ILD患者中甲状腺功能低下和DM的患病率显著更高.
- 建议对ILD患者进行甲状腺功能低下和DM的查,因为它们的高发生率和对疾病进展的潜在影响.
- 可能存在双向关系,如果怀疑,建议在患有甲状腺功能低下症和甲状腺癌的患者中查ILD.
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