血管内治疗后72小时内血压波动和急性缺血性中风患者的预后
Mingfeng Tao1, Yongxin Li1, Ya Peng2
1Department of Neurology, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong, China.
概括
在急性缺血性中风 (AIS) 进行内血管治疗 (EVT) 后控制血压 (BP) 波动至关重要. 在EVT后72小时内,较大的血压变化与较差的患者结局有关.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 临床试验 临床试验
背景情况:
- 急性缺血性中风 (AIS) 管理通常涉及内血管治疗 (EVT).
- 在EVT后的血压 (BP) 管理对于患者的预后至关重要.
- 在EVT之后,BP组件波动对AIS结果的影响需要进一步调查.
研究的目的:
- 为了研究血压成分波动之间的关系,在EVT和AIS患者预后后72小时内.
- 为了确定抽缩血压 (SBP),腹缩血压 (DBP) 或平均动脉压 (MAP) 的变化是否会影响结果.
- 与平均BP值相比,评估BP波动的预测能力.
主要方法:
- 对283名接受EVT的AIS患者进行前性多中心研究.
- 在EVT后72小时内收集的BP数据.
- 主要结局:90天后修改了兰金表 (mRS);次要结局:3个月后死亡或严重残疾 (mRS3-6).
主要成果:
- SBP波动的最高三位数与初级 (OR=1.747) 和二级 (OR=1.889) 结果差的几率增加有关.
- DBP (OR=1.914) 和MAP (OR=1.759) 的波动与较差的初级结果有关.
- 血压波动在预测预后方面表现出显著的歧视能力.
结论:
- 在EVT后72小时内增加SBP,DBP和MAP波动与AIS患者不良临床结果的风险更高相关.
- 管理血压波动,以及平均血压,可能会改善AVT后AIS患者的预后.
- 这项研究强调了监测常规实践中血压变化的临床重要性.
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