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马达加斯加急性暴露于细颗粒物 (PM2.5) 的咳发病率:试点研究

Alexandra J Zimmer1,2, Lai Yu Tsang3, Gisèle Jolicoeur4

  • 1Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada.

PLOS global public health
|July 26, 2024
PubMed
概括

这项试点研究发现,较高的细颗粒物 (PM2.5) 含量立即与马达加斯加农村咳频率的增加有关. 客观监测显示,咳增加了39%,PM2.5暴露增加了10倍.

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Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
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